ACCELERATED clinical trials will be launched in West Africa to speed the search for a treatment for the deadly Ebola virus, Doctors Without Borders says.
THE international humanitarian group says it will host clinical trials starting next month in three Ebola treatment centres using experimental drugs that haven’t been through the usual lengthy process of study with animals and healthy people.
Separate trials will be led by three different research partners and involve the UN World Health Organisation and health officials in affected countries. “If we’re going to find a treatment, we have to do it now – which is why we have to accelerate these trials,” said Peter Horby, the chief investigator for the trial led by Oxford University. Oxford’s trial will test the antiviral drug brincidofovir in Liberia. France’s National Institute of Health and Medical Research will conduct a trial using the antiviral drug favipiravir in Gueckedou, Guinea, and the Antwerp Institute of Tropical Medicine will test convalescent whole blood and plasma therapy in Guinea. Results from some of the trials are expected by February or March. The largest-ever outbreak of Ebola has raged for than eight months, killing more than 5000 people and infecting more than 14,000 in West Africa. The UN has appointed an Ebola chief and various governments have set up clinics. But medical teams are stretched thin and the UN health agency WHO says there are not enough foreign medical workers. There are no established drugs for Ebola. Human testing of a handful of experimental drugs for Ebola has begun on several continents. The current outbreak kills between 50 and 80 per cent of those infected in West Africa, according to Doctors Without Borders.